Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Isl1  ISL1 transcription factor, LIM/homeodomain   (Synonyms: Islet 1)
Results	Reference
1	J:37641 Ahlgren U, Pfaff SL, Jessell TM, Edlund T, Edlund H, Independent requirement for ISL1 in formation of pancreatic mesenchyme and islet cells. Nature. 1997 Jan 16;385(6613):257-60
1	J:207610 Akiyama R, Kawakami H, Taketo MM, Evans SM, Wada N, Petryk A, Kawakami Y, Distinct populations within Isl1 lineages contribute to appendicular and facial skeletogenesis through the beta-catenin pathway. Dev Biol. 2014 Mar 1;387(1):37-48
1	J:57072 Apelqvist A, Li H, Sommer L, Beatus P, Anderson DJ, Honjo T, Hrabe de Angelis M, Lendahl U, Edlund H, Notch signalling controls pancreatic cell differentiation. Nature. 1999 Aug 26;400(6747):877-81
1	J:169957 Chen L, Fulcoli FG, Tang S, Baldini A, Tbx1 regulates proliferation and differentiation of multipotent heart progenitors. Circ Res. 2009 Oct 23;105(9):842-51
1	J:297083 De Zoysa P, Liu J, Toubat O, Choi J, Moon A, Gill PS, Duarte A, Sucov HM, Kumar SR, Delta-like ligand 4-mediated Notch signaling controls proliferation of second heart field progenitor cells by regulating Fgf8 expression. Development. 2020 Sep 11;147(17):dev185249
1*	J:72022 Esni F, Johansson BR, Radice GL, Semb H, Dorsal pancreas agenesis in N-cadherin- deficient mice. Dev Biol. 2001 Oct 1;238(1):202-12
1	J:158231 Francius C, Clotman F, Dynamic expression of the Onecut transcription factors HNF-6, OC-2 and OC-3 during spinal motor neuron development. Neuroscience. 2010 Jan 13;165(1):116-29
1	J:271432 Gibbs BC, Shenje L, Andersen P, Miyamoto M, Kwon C, beta1-integrin is a cell-autonomous factor mediating the Numb pathway for cardiac progenitor maintenance. Biochem Biophys Res Commun. 2018 Jun 2;500(2):256-260
1	J:172023 Guo C, Sun Y, Zhou B, Adam RM, Li X, Pu WT, Morrow BE, Moon A, Li X, A Tbx1-Six1/Eya1-Fgf8 genetic pathway controls mammalian cardiovascular and craniofacial morphogenesis. J Clin Invest. 2011 Apr 1;121(4):1585-95
1*	J:104894 Jacquemin P, Yoshitomi H, Kashima Y, Rousseau GG, Lemaigre FP, Zaret KS, An endothelial-mesenchymal relay pathway regulates early phases of pancreas development. Dev Biol. 2006 Feb 1;290(1):189-99
1	J:59312 Jensen J, Pedersen EE, Galante P, Hald J, Heller RS, Ishibashi M, Kageyama R, Guillemot F, Serup P, Madsen OD, Control of endodermal endocrine development by Hes-1. Nat Genet. 2000 Jan;24(1):36-44
1	J:186421 Klaus A, Muller M, Schulz H, Saga Y, Martin JF, Birchmeier W, Wnt/beta-catenin and Bmp signals control distinct sets of transcription factors in cardiac progenitor cells. Proc Natl Acad Sci U S A. 2012 Jul 3;109(27):10921-6
1	J:330214 Lania G, Franzese M, Adachi N, Bilio M, Flore G, Russo A, D'Agostino E, Angelini C, Kelly RG, Baldini A, A phenotypic rescue approach identifies lineage regionalization defects in a mouse model of DiGeorge syndrome. Dis Model Mech. 2022 Sep 1;15(9):dmm049415
1	J:73278 Li H, Edlund H, Persistent expression of hlxb9 in the pancreatic epithelium impairs pancreatic development. Dev Biol. 2001 Dec 1;240(1):247-53
1	J:178050 Liang X, Song MR, Xu Z, Lanuza GM, Liu Y, Zhuang T, Chen Y, Pfaff SL, Evans SM, Sun Y, Isl1 is required for multiple aspects of motor neuron development. Mol Cell Neurosci. 2011 Jul;47(3):215-22
1	J:160496 Makki N, Capecchi MR, Hoxa1 lineage tracing indicates a direct role for Hoxa1 in the development of the inner ear, the heart, and the third rhombomere. Dev Biol. 2010 May 15;341(2):499-509
1	J:329978 Maruyama K, Miyagawa-Tomita S, Haneda Y, Kida M, Matsuzaki F, Imanaka-Yoshida K, Kurihara H, The cardiopharyngeal mesoderm contributes to lymphatic vessel development in mouse. Elife. 2022 Oct 5;11:e81515
1	J:150755 Oh S, Huang X, Liu J, Litingtung Y, Chiang C, Shh and Gli3 activities are required for timely generation of motor neuron progenitors. Dev Biol. 2009 Jul 15;331(2):261-9
1	J:228847 Ramsbottom SA, Sharma V, Rhee HJ, Eley L, Phillips HM, Rigby HF, Dean C, Chaudhry B, Henderson DJ, Vangl2-regulated polarisation of second heart field-derived cells is required for outflow tract lengthening during cardiac development. PLoS Genet. 2014 Dec;10(12):e1004871
1	J:303312 Rayon T, Stamataki D, Perez-Carrasco R, Garcia-Perez L, Barrington C, Melchionda M, Exelby K, Lazaro J, Tybulewicz VLJ, Fisher EMC, Briscoe J, Species-specific pace of development is associated with differences in protein stability. Science. 2020 Sep 18;369(6510)
1	J:213214 Shenje LT, Andersen P, Uosaki H, Fernandez L, Rainer PP, Cho GS, Lee DI, Zhong W, Harvey RP, Kass DA, Kwon C, Precardiac deletion of Numb and Numblike reveals renewal of cardiac progenitors. Elife. 2014;3:e02164
1	J:309602 Soh BS, Buac K, Xu H, Li E, Ng SY, Wu H, Chmielowiec J, Jiang X, Bu L, Li RA, Cowan C, Chien KR, N-cadherin prevents the premature differentiation of anterior heart field progenitors in the pharyngeal mesodermal microenvironment. Cell Res. 2014 Dec;24(12):1420-32
1	J:278511 Soldatov R, Kaucka M, Kastriti ME, Petersen J, Chontorotzea T, Englmaier L, Akkuratova N, Yang Y, Haring M, Dyachuk V, Bock C, Farlik M, Piacentino ML, Boismoreau F, Hilscher MM, Yokota C, Qian X, Nilsson M, Bronner ME, Croci L, Hsiao WY, Guertin DA, Brunet JF, Consalez GG, Ernfors P, Fried K, Kharchenko PV, Adameyko I, Spatiotemporal structure of cell fate decisions in murine neural crest. Science. 2019 Jun 7;364(6444)
1	J:222450 Uribe V, Badia-Careaga C, Casanova JC, Dominguez JN, de la Pompa JL, Sanz-Ezquerro JJ, Arid3b is essential for second heart field cell deployment and heart patterning. Development. 2014 Nov;141(21):4168-81
1	J:290253 Vigouroux RJ, Cesar Q, Chedotal A, Nguyen-Ba-Charvet KT, Revisiting the role of Dcc in visual system development with a novel eye clearing method. Elife. 2020 Feb 25;9:e51275
1	J:279272 Wang JJ, Liu HX, Song L, Li HR, Yang YP, Zhang T, Jing Y, Isl-1 positive pharyngeal mesenchyme subpopulation and its role in the separation and remodeling of the aortic sac in embryonic mouse heart. Dev Dyn. 2019 Sep;248(9):771-783
1	J:244345 Yuan X, Qi H, Li X, Wu F, Fang J, Bober E, Dobreva G, Zhou Y, Braun T, Disruption of spatiotemporal hypoxic signaling causes congenital heart disease in mice. J Clin Invest. 2017 Jun 01;127(6):2235-2248